python - Convert a letter in string to different letters with multiple output -


so have dna sequence

dna = "tannnt"

where n = ["a", "g", "c", "t"]

i want have possible output of taaaat, taaagt, taaact, taaatt..... , on.

right online found solution of permutations can perms = [''.join(p) p in permutations(n, 3)] iterate dna sequence ta + perms + t

but wonder if there easier way this, because have lot more dna sequences , make take lot more time hard code it.

edit:

the hard code part in have state 

n1 = [''.join(p) p in permutations(n, 1)] n2 = [''.join(p) p in permutations(n, 2)] n3 = [''.join(p) p in permutations(n, 3)]

then in n3:

key = "ta" + n3[i] + "t"

since sequence quite long, don't want count how many consecutive n have in sequence , want see if there better way this.

you can use permutation results format string like:

code:

import itertools import re  def convert_sequence(base_string, target_letter, perms):     regex = re.compile('(%s+)' % target_letter)     match = regex.search(base_string).group(0)     pattern = regex.sub('%s', base_string)     return [pattern % ''.join(p) p in it.permutations(perms, len(match))]

test code: 

print(convert_sequence('tannnt', 'n', ['a', 'g', 'c', 't']))

results:

['taagct', 'taagtt', 'taacgt', 'taactt', 'taatgt',   'taatct', 'tagact', 'tagatt', 'tagcat', 'tagctt',   'tagtat', 'tagtct', 'tacagt', 'tacatt', 'tacgat',   'tacgtt', 'tactat', 'tactgt', 'tatagt', 'tatact',   'tatgat', 'tatgct', 'tatcat', 'tatcgt']

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